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The pros and cons of SSRI antidepressants

The new generation of anti-depressants, SSRIs, were hailed as wonder drugs when they were first developed, but, in recent years, there has been much concern about possible withdrawal symptoms and a possible link between SSRI use and an increase in suicidal thoughts. How concerned should we be about SSRIs? Dr George Masterton reviews the evidence. Read…

PONDERING OBESITY: THERAPEUTIC TARGETS IN BRAIN AND FAT

Two recent areas of research into obesity have caused considerable scientific and popular interest; the role of the brain in controlling appetite and metabolism, and the emerging biology of adipose tissue. These two fields have converged with recognition that the fat and other metabolic tissues send potent signals to the brain and vice versa. Prof Jonathan Seckl reviews the emerging evidence. Read…